4" is good for the concrete. Consider a vapor barrier and insulation under the slab.
It will help with any moisture that could come through the concrete and be very beneficial if you choose to heat or cool the area. Granted it won't take much for a 10 X 12 shed.
It will help with any moisture that could come through the concrete and be very beneficial if you choose to heat or cool the area. Granted it won't take much for a 10 X 12 shed.