I have installed small units like this and I see no reason larger ones cannot be also. My concern would be that the tank is able to support itself because there is no soil to hold it's shape. I suggest you find a model you're interested in and contact the factory rep and verify that it can be installed as you propose. They may even have engineered drawings that will satisfy your inspector.
You also said the 2nd floor is now going to be piped to the septic- I assume you verified the tank and drain field will support the additional load.
You also said the 2nd floor is now going to be piped to the septic- I assume you verified the tank and drain field will support the additional load.