Well, I wouldn't even think about notching the truss.
Have a fabricating shop make a new piece up for the factory duct extension to go to 2 1/4 by 12, or 2 1/4 by 14. And then get a transition or have then make one from that size to 8" round.
Have a fabricating shop make a new piece up for the factory duct extension to go to 2 1/4 by 12, or 2 1/4 by 14. And then get a transition or have then make one from that size to 8" round.