Well, I'll admit I still need to read up and learn more about the WC figures. I've looked before and to be honest, I gave up as it was a bit confusing to me. Maybe I should read up again....
That said, I decided to just go for it and eliminate the large trunk in this area and replaced it with two 7" round pipe and two 6" round pipe sections with Home Run takeoff's from the furnace. I installed dampers at each takeoff at the furnace. Just finished the last little bit up today and what a difference it seems to have made. Prior to this the lower access panel on lower section of furnace would vibrate, not noticeable unless next to it, but that is now gone. Air flow seems better in each room and I was able to come off one 6" pipe and one 7" pipe and I went a few feet over and added ceiling registers in the basement, so if I ever want, I can open them for a bit of air flow. I do plan to add a return air in the basement as well.
At some point, I think I'm going to do what I can to redo the other half of the house, if this is what I can expect....honestly seems sooo much better. I'm curious if it changes energy bills any. When I started it seemed the AC was running almost non-stop on a low 90* day we had. Today it's almost 100* and I've noticed it shut off several times! Does that really make since?