Begin your layout so that the tile falls under the center of the door when it is closed. Your layout as it exists is slightly off-balance with the room but it isn't a big deal. I'm betting you are trying to center-up a grout line with the center-line of the toilet...that's the way I would do it also in this case.
Doing exactly what you are showing in you photo works great because:
1. You have a corner near the toilet that will skew the balance anyway.
2. When the vanity is re-installed you won't notice the skewed balance on that side of the room.
3. If the door routinely stands open when the room is not in use as most
normally do, the open door will also disrupt any noticeable imbalance.
My suggestion is "GO FOR IT".
Doing exactly what you are showing in you photo works great because:
1. You have a corner near the toilet that will skew the balance anyway.
2. When the vanity is re-installed you won't notice the skewed balance on that side of the room.
3. If the door routinely stands open when the room is not in use as most
normally do, the open door will also disrupt any noticeable imbalance.
My suggestion is "GO FOR IT".
