From a practical standpoint, it's good to run hard duct on rough-in stage but on refit jobs it makes flex duct the better choice.
On long suspended spans, it must be supported with the 2" wide straps as opposed the the smaller width stuff or even plumber's tape that I have often seen. Every 16" or 2' is best but no longer than 4' is a good arbitrary maximum for support spans. If done properly, it'll look good and stay good. The ones you see sagging weren't installed properly.
To each his own, hard duct is always better quality but if you aren't doing it yourself, that type of installation will cost more than most people want to pay.