No offense to anyone, but this has gone from a moderately messy octopus design, to a complete cluster$%^$ in the making
Run romex all the way to the panel. Every splice you make is a potential for failure.
Avoid splice boxes in the attic unless it's a really accessible attic.
As far as drywall patch, it almost as easy to run 2 wire as it is to run one. Take the easiest paths available. Also, drywall patch is easy in closets because no one really sees them. Actually, drywall patch is pretty easy most anywhere. I bet a guy would come in and patch the whole house for under $200 if you save all the pieces.
Be aware that if you run the cable thru the "new" wall, it will be a surprise/nightmare if someone wants to eliminate that in the future. I like to keep things "stock".