I'll be setting up a mobile home on my property, which will have an artesian well. I live in the northeast, so the Pressure tank will need to be inside the trailer. Just wasn't sure how the correct way to run the water line into the home is to prevent freezing. Do I just wrap the hell out of it with insulation?
No way to know because no one knows where you live.
When I lived in NH we made a box out of vinyl lumber leaving one side off but predrilled holes in the last piece , installed heat tape, insulated with fiberglass pipe wrap, then installed the last piece to seal it all in.
Make sure the bottom of the vinyl is below grade at least 6".
I used vinyl because any type of wood even pressure treated will rot over time and termites would then have a ladder to get into the house.
I hope you plan on adding skirting. Just stopping the wind from getting in under there will make a big differance in inside temp. less chance of pipes freezing.