Talk about frustrating...I started laying tile in my new construction home this weekend. B=My broither-in-law, who has lots of tile laying experience, helped me out.
One big problem that we experienced was that the thinset wouldn't stick to the backerboard when trying to spread it. We were using Shaw Multiset and FiberRock backerboard. We had to mix it so that it was a little on the wet side to make it stick (too wet in his opinion).