Mix the thinset a little loose, but still stiff enough so that when you spread it, it holds the ridges without collapsing, use a 1/4x1/4" square notched trowel, set the board down on it, walk on it getting it down good, now screw it down tight every 6 to 8" throughout, use the Hardie screws and their square bit that comes in the box, a good corded drill or drywall gun works fine for this, screw it down so that the screws set themselves flush with the board.
Tape and thinset the seams while tiling with a good modified thinset.