Latex versus Oil On Bare Metal. Does Latex Cut It?
It really varies by company anymore. For the most part the oil primers, especially red oxide will have the edge in corrosion prevention. That said we sell the Virginia Department of Transportation Davis Acrylic DTM with Davis W101 Acrylic Red Oxide DTM Primer. That primer has better rust inhibitive properties than the oil. It did originate in the railroad industry for coating box cars though. We've done several roofs with it, fully stripped down to bare metal and primed and top coated with the DTM products. Not one has had any rust issues.
Using a good Acrylic products on an interior application shouldn't be much of an issue unless there are existing rust problems. I've never had anyone use a good acrylic on metal that has any any issues this way. Exterior is another matter. Depending on what you are doing, proper priming is essential to prevent rust.