Hello,
I'm new to this forum and as you will soon see very new to the idea of HVAC.
I am building a man cave in my basement with the intentions of turning it into my own little cigar club. As you can imagine if i'm not able to vent out the smoke and keep the house from smelling like a fine stoagie my wife will

eh hem. Flip out...
Anyway. I have a drop ceiling already in the basement and my intentions are to retain that. I have a 4 inch space between the top of my drop ceiling hangers and the the floor joists. I am looking at a 1200 cfm fan which will more than adequately meet my cfm needs to meet the target air replacements per hour that a great website online told me i needed..
That said the fan i'm looking at has a 12 inch round inlet. I was wondering if i could run a 3.25 x 10 inch duct with about 2-3 registers for about 20 feet then put a transition to an 8 inch round for about 10- 15 feet then into a 8 to 12 inch round transition which would end at the inline fan itself about 15 feet away. First would this work, and 2 how bad would performance be. I will be creating negative airflow by opening a damper into an existing space.
I hope you all can help me out on this.
Tim